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![Logo des CRC DECIDE](https://static.wixstatic.com/media/cb4479_efa008d3753546ea807b63accfe3c5aa~mv2.png/v1/crop/x_0,y_0,w_3033,h_2800/fill/w_116,h_107,al_c,q_85,usm_0.66_1.00_0.01,enc_auto/Rudel_DECIDE_LOGO_final_RGB_White-01.png)
Projects
For more information about the individual projects, please click at the corresponding title/box.
Project RA-A
RA A: From initiation to established infection
![Project A01](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A01
Age-dependent airway epithelial determinants of severe human respiratory viral infections
![Project A02](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A02
Age-dependent intestinal epithelial determinants of infections with enteropathogenic Escherichia coli & Campylobacter jejuni
![Project A03](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A03
Molecular decision points that determine colonisation & infection risk in neonatal skin
![Project A04](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_189,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A04
Epithelial physiology & immune status as decision points in the initiation of toxin induced Clostridioides difficile colitis
![Project A05](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A05
Mechanisms of infection control by pathogen-educated epithelial-immune cell circuits
![Project A06](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A06
Pulmonary Aspergillus infection progression determined by alveolar macrophages as initial responders
![Project A07](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A07
Mechanisms facilitating local herpes simplex virus replication and control in the female reproductive tract
![Project A08](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A08
Mechanisms of Chlamydia & human papillomavirus coinfection in metaplastic tissue of the uterine cervix
![Project A09](https://static.wixstatic.com/media/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png/v1/fill/w_189,h_188,q_90/cb4479_48ec5b5cb092497e9b9761053b876355~mv2.png)
A09
Molecular decision points that determine colorectal cancer colonisation by Fusobacterium nucleatum
Project RA-B
RA B: From active infection to persistence
![Project B01](https://static.wixstatic.com/media/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png)
B01
Mechanisms driving chlamydial persistence & ascending infection in the female reproductive tract
![Project B03](https://static.wixstatic.com/media/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png)
B03
Mechanisms driving persistence of Yersinia pseudotuberculosis in lymphoid tissues of the intestinal tract
![Project B04](https://static.wixstatic.com/media/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png)
B04
Systems biology approach to identify key molecular decision
points for intracellular
persistence during infection
points for intracellular
persistence during infection
![Project B05](https://static.wixstatic.com/media/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png/v1/fill/w_189,h_188,q_90/cb4479_5de8ae6bb3d94f56ba0cd7e7f12152d3~mv2.png)
B05
Uncovering host mechanisms underlying Salmonella persistent infection of intestinal
epithelial cells
epithelial cells
Projects RA-C
RA C: From localised infection to pathogen spreading
![Project C01](https://static.wixstatic.com/media/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png)
C01
Mechanisms underlying
unconventional T cell function as decision points to prevent microbial spread via the lymph
unconventional T cell function as decision points to prevent microbial spread via the lymph
![Project C02](https://static.wixstatic.com/media/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png)
C02
Metabolic control of innate & adaptive immune responses to
cutaneous Staphylococcus aureus infection
cutaneous Staphylococcus aureus infection
![Project C03](https://static.wixstatic.com/media/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png)
C03
The lung as a pathogen-specific entry site for systemic infection
![Project C04](https://static.wixstatic.com/media/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png/v1/fill/w_189,h_188,q_90/cb4479_d1bf85f286ea4803aa774bc06a14f534~mv2.png)
C04
Molecular decision points underlying the systemic spreading of Staphylococcus aureus
Central Projects
Central Projects
![Project MGK](https://static.wixstatic.com/media/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png)
MGK
Integrated Research Training Group “DECIDE”
(IRTG DECIDE)
(IRTG DECIDE)
![Project INF](https://static.wixstatic.com/media/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png)
INF
Data management platform to facilitate data integration & in silico identification of decision points in infection
![Project Z01](https://static.wixstatic.com/media/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png/v1/fill/w_188,h_188,q_90/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png)
Z01
Central Tasks of the Collaborative Research Centre
![Project Z02](https://static.wixstatic.com/media/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png/v1/fill/w_189,h_188,q_90/cb4479_0e4008b2f82c4c189a51dcc42cc8f1b4~mv2.png)
Z02
Temporal and spatial single-cell genomics to map decision points in infection
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